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claritromycine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01F - Macrolides, Lincosamides And Streptogramins -> J01FA - Macrolides -> J01FA09 - Clarithromycin
Administration category: Free Medicine group: antibacterial Brand name: Klacid

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
po
Dosage:
min. 250mg 2 dd to max. 500mg 2 dd
Comments:

maximale dagdosis bij CF: 1000 mg 2 dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: po
GFR:
10 - 30
Dosage:
50%
Renal elimination: 20-40%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: 250 mg 2 dd of 500 mg 1 dd.

Hemo dialysis: 250 mg 2 dd of 500 mg 1 dd.

CAV / VVHD: 250 mg 2 dd of 500 mg 1 dd.

Interactions

Interaction with (ATC): Expected effect:
Interaction with (ATC):
N03AF01 - Carbamazepine
Expected effect:
verhoging plasmaconcentratie carbamazepine
Interaction with (ATC):
L04AD01 - Ciclosporin
Expected effect:
verhoging ciclosporineconcentratie in volbloed
Interaction with (ATC):
C01AA05 - Digoxin
Expected effect:
verhoging plasmaconcentratie digoxine
Interaction with (ATC):
L04AD02 - Tacrolimus
Expected effect:
verhoging plasmaconcentratie tacrolimus
Interaction with (ATC):
R03DA04 - Theophylline
Expected effect:
verhoging plasmaconcentratie theofylline
Interaction with (ATC):
R06AX12 - Terfenadine
Expected effect:
toename cardiotoxiciteit
Interaction with (ATC):
A03FA02 - Cisapride
Expected effect:
toename cardiotoxiciteit
Interaction with (ATC):
C01BA03 - Disopyramide
Expected effect:
toename cardiotoxiciteit
Interaction with (ATC):
J05AE - Protease Inhibitors
Expected effect:
verhoging plasmaconcentratie proteaseremmers en claritromycine

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1260.3
Updated: 06/16/2019 - 20:05
Status: Published

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